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李 凤(副教授)

所属单位:天津大学化工学院

担任职务:副教授

擅长领域:

联系方式:022-27403389 邮箱:登录后查看

李 凤,副教授, DNA/聚合物杂化动态组装体系的构建和生物应用 实验室链接

主要成就

1 . Feng Li +, Shuai Li+, Xiaocui Guo, Yuhang Dong, Chi Yao, Yangping Liu, Yuguang Song, Xiaoli Tan, Lizeng Gao, Dayong Yang*. Chiral carbon dots mimicking topoisomerase I to enantioselectively mediate topological rearrangement of supercoiled DNA . Angew. Chem. Int. Ed. 2020. 2. Feng Li , Tianyu Li, Chenxing Sun, Jiahao Xia, Yang Jiao, and Huaping Xu*. “Selenium-Doped Carbon Quantum Dots (Se-CQDs) for Free Radical Scavenging.” Angew. Chem. Int. Ed. 2017, 129, 10042-10046. 3. Feng Li +, Yiye Li+, Xiao Yang, Xuexiang Han, Yang Jiao, Taotao Wei, Dayong Yang, Huaping Xu*, Guangjun Nie*. Highly Fluorescent Chiral N-S-Doped Carbon Dots from Cysteine Affect Cellular Energy Metabolism. Angew. Chem. Int. Ed .2018.9, 2377-2382. 4. Xiaocui Guo+, Feng Li +, Lihui Bai, Wenting Yu, Xue Zhang, Yi Zhu, Dayong Yang*. Gene Circuit Compartment on Nano-interface Facilitates Cascade Gene Expression . J. Am. Chem. Soc . 2019. 5 Feng Li +, Jianpu Tang+, Jinhui Geng, Dan Luo, Dayong Yang*. Polymeric DNA Hydrogel: Design, Synthesis and Applications . Progress in Polymer Science , 2019. 6. Feng Li +, Xue Zhang+, Shuxian Hu+, Zhaoyue Lv, Jigang Lv, Wenting Yu, Xihan Xu, Dayong Yang*. Bioinspired Mechanically Responsive Hydrogel upon Redox Mediated by Dynamic Coordination between Telluroether and Platinum Ions . Chemistry of Materials , 2020. 7. Feng Li +, Wenting Yu+, Xue Zhang, Xiaocui Guo, Xihan Xu, Xiaolei Sun, Dayong Yang*. Preparation of Biomimetic Gene Hydrogel via Polymerase Chain Reaction for Cell-Free Protein Expression . Science China Chemistry , 2019. 8. Feng Li , Xiao Zhao, Hai Wang, Ruifang Zhao, Tianjiao Ji, He Ren, Gregory J. Anderson, Guangjun Nie*, and Jihui Hao*. “Multiple Layer-by-layer Lipid-polymer Hybrid Nanoparticles for Improved FOLFIRINOX Chemotherapy in Pancreatic Tumor Models.” Adv. Funct. Mater. 2015,25, 788-798. 9. Feng Li , Jing Wang, Shuqing Sun*, Hai Wang, Zhiyong Tang, and Guangjun Nie*. “Facile Synthesis of pH-sensitive Germanium Nanocrystals with High Quantum Yield for Intracellular Acidic Compartment Imaging.” Small , 2015, 16, 1954-1961. 10. Feng Li +, Yuhang Dong+, Zhikun Zhang+, Man Lv+, Zhi Wang, Xinhua Ruan, Dayong Yang*. A recyclable biointerface based on cross-linked branched DNA nanostructures for ultrasensitive nucleic acid detection . Biosensors and Bioelectronics , 2018, 117, 562-566. 11. Xiao Zhao+, Feng Li +, Yiye Li, Hai Wang, He Ren, Jing Chen, Guangjun Nie*, and Jihui Hao*. “Co-delivery of HIF1α siRNA and Gemcitabine via Biocompatible Lipid-polymer Hybrid Nanoparticles for Effective Treatment of Pancreatic Cancer.” Biomaterials , 2015, 46, 13-25. 12. Feng Li , Wei Cao, Lu Wang, and Huaping Xu*. “Near-Infrared Light Stimuli-responsive Synergistic Therapy Nanoplatforms Based on the Coordination of Tellurium-containing Block Polymer and Cisplatin for Cancer Treatment.” Biomaterials , 2017, 133, 208-218. 13. Feng Li , Jing Wang, Yuming Lai, Chong Wu, and Shuqing Sun*. “Ultrasensitive and Selective Detection of Copper (II) and Mercury (II) Ions by Dye-Coded Silver Nanoparticle-Based SERS Probes.” Biosens. Bioelectron . 2013, 39, 82-87. 14. Qianmin Ma+, Feng Li +, Jianpu Tang, Ke Meng, Xihan Xu, Dayong Yang*. Luminescent ultralong microfiber prepared via supramolecular self-assembly of lanthanide and thymidine in water . Chemistry-A European Journal , 2018, 24, 18890-18896. DOI: 10.1002/chem.201804785. 15 . Feng Li *, Dayong Yang, Huaping Xu*. Nonmetal heteroatom doped carbon dots: synthesis and property . Chemistry-A European Journal , 2018, 24, 1-13. DOI:10.1002/chem.201802793. 16 . Feng Li , Tianyu Li, Xuexiang Han, Hao Zhuang, Guangjun Nie, and Huaping Xu*. “Nanomedicine Assembled by Coordinated Selenium-Platinum Complexes Can Selectively Induce Cytotoxicity in Cancer Cells by Targeting the Glutathione Antioxidant Defense System.” ACS Biomater-SCI. Eng. 2019. 17. Chenxing Sun, Shaobi Ji, Feng Li *, and Huaping Xu*. “Diselenide-Containing Hyperbranched Polymer with Light-Induced Cytotoxicity.” ACS Appl. Mater. Interfaces , 2017, 9, 12924-12929. 18. Jiaojiao Zhang+, Feng Li +, Dayong Yang*. DNA: From carrier of genetic information to polymeric materials. Transactions of Tianjin University , 2019. 19. Xiaocui Guo, Lihui Bai, Feng Li , Wilhelm Huck, Dayong Yang*. Branched DNA architectures via PCR‐based assembly as gene compartment for cell‐free gene expression reactions . ChemBioChem , 2019. DOI: 10.1002/cbic.201900094. 20. Huaixin Zhao+, Chunxia Liu+, Zi Gu, Luxi Dong, Feng Li , Chi Yao, Dayong Yang*. Persistent luminescent nanoparticles containing hydrogel for targeted, sustained and autofluorescence-free tumor metastasis imaging . Nano Letters , 2019. 21. Lu Yang+, Chi Yao+, Feng Li , Yuhang Dong, Zhikun Zhang, and Dayong Yang*. Synthesis of branched DNA scaffolded super-nanoclusters with enhanced antibacterial performance . Small , 2018, 14, 1800185. 22. Jiahao Xia, Feng Li , Shaobo Ji, and Huaping Xu*. “Selenium-functionalized Graphene Oxide that Can Modulate the Balance of Reactive Oxygen Species.” ACS Appl. Mater. Interfaces , 2017, 9, 21413-21421. 23. Yuming Lai, Feng Li , and Shuqing Sun*. “Controlled Surface Enhanced Resonance Raman Scattering (SERRS) in Biological Environment.” Integr. Ferroelectr. 2013, 146, 88-98. 24. Tianyu Li, Feng Li , Wentian Xiang, Yu Yi, Yuyan Chen, Liang Cheng, Zhuang Liu,and Huaping Xu*. “Selenium-containing Amphiphiles Reduced and Stabilized Gold Nanoparticles: Kill Cancer Cells via Reactive Oxygen Species.” ACS Appl. Mater. Interfaces , 2016, 8, 22106-22112. 25. Wei Cao, Feng Li , Ruofan Chen, and HuapingXu*. “Tellurium-Containing Nanoparticles for Controlled Delivery of Cisplatin Based on Coordination Interaction.” RSC Advances , 2016, 6, 94033-94037. 26. Fuqiang Fan, Lu Wang, Feng Li , Yu Fu, and Huaping Xu*. “Stimuli-Responsive Layer-by-Layer Tellurium-Containing Polymer Films for Combination of Chemotherapy and Photodynamic Therapy.” ACS Appl. Mater. Interfaces, 2016, 8, 17004-17010. 27. Weiqiang Zhou, Lu Wang, Feng Li , Weina Zhang, Wei Huang, Fengwei Huo*, and HuapingXu*.“Selenium-containing Polymer@metal-organic Frameworks Nanocomposites as Efficientmulti-responsive Drug Delivery System.” Adv. Funct. Mater . 2017, 27, 1605465. 28. Lu Yang, Chi Yao, Feng Li , Yuhang Dong, Zhikun Zhang, and Dayong Yang*. Synthesis of Branched DNA Scaffolded Super-nanoclusters with Enhanced Antibacterial Performance. Small , 2018, 16,1800185. 29. Tianyu Li, Wentian Xiang, Feng Li , and Huaping Xu.Self-assembly regulated anticancer activity of platinum coordinated selenomethionine. Biomaterials , 2017, 157, 17-25. 30. Hai Wang, Ruifang Zhao, Yiye Li, Huiyu Liu, Feng Li , Yuliang Zhao, and Guangjun Nie*. “Aspect Ratios of Gold Nanoshell Capsules Mediated Melanoma Ablation by Synergistic Photothermal Therapy and Chemotherapy.” Nanomedicine , 2015, 12, 439-448. 31. Suping Li, Yinlong Zhang, Jing Wang, Ying Zhao, Tianjiao Ji, Xiao Zhao, Yanping Ding, Xiaozheng Zhao, Ruifang Zhao, Feng Li , Xiao Yang, Shaoli Liu, Zhaofei Liu, Jianhao Lai, Andrew K. Whittaker, Gregory J. Anderson, Jingyan Wei, and Guangjun Nie*. Nanoparticle-mediated Local Depletion of Tumour-associated Platelets Disrupts Vascular Barriers and Augments Drug Accumulation in Tumours. Nature Biomed. Eng. 2017, 8, 667-679. 实验室链接